Searchable abstracts of presentations at key conferences in endocrinology

Endocrine Abstracts

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ea0092op-06-04 | Oral Session 6: Pregnancy | ETA2023

Changes in TSH suppression during pregnancy reveals novel mechanism for increased thyroid hormone production: comparison between euthyroid and thyroidectomized pregnant women

Scuto Andrea , Tumino Dario , Gambero Federica , Di Benedetto Guenda , Piticchio Tommaso , Malandrino Pasqualino , Frasca Francesco

Objective: Clarify mechanisms determining thyroid homeostasis during pregnancy at hypothalamic-pituitary level.Methods: Retrospective analysis of 251 pregnant women. 220/251 euthyroid without thyroxine therapy (Group 1), 31/251 thyroidectomized under thyroxine replacement therapy (Group 2). Patients under thyroxine replacement therapy with a TSH between 0.4 and 4.0 were included in the study. Patients with combined T3/T4 therapy were excluded.<p clas...
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ea0092op-10-03 | Oral Session 10: Novel diagnostics in Thyroid cancer | ETA2023

KI67 proliferative index, but not mitotic count and necrosis, is a prognostic factor in patients with medullary thyroid cancer: a single-center retrospective analysis according to the 2022 who pathological classification

Prinzi Antonio , Bosco Agata , Mirone Alessandro , Tumino Dario , Di Benedetto Guenda , Gambero Federica , Bartoloni Giovanni , Frasca Francesco , Belfiore Antonino , Malandrino Pasqualino

Background: The 2022 WHO Classification of Endocrine and Neuroendocrine Tumors has introduced, as other neuroendocrine neoplasms, new pathological features to classify medullary thyroid carcinoma (MTC) in low/high grade. However, whether it can be reliable in clinical practice should be confirm by further studies.Aim: To verify the predictive value of the 2022 WHO grading system in patients with MTC.Materials and Methods: Tumor tis...
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ea0092ps3-29-03 | Treatment 2 | ETA2023

TKIS for advanced thyroid cancer increase tsh levels in thyroidectomized patients: A meta-analysis

Piticchio Tommaso , Belfiore Antonino , Malandrino Pasqualino , Trimboli Pierpaolo , Gambero Federica , Scuto Andrea , Volpe Salvatore , Di Benedetto Guenda , Dario Tumino , Le Moli Rosario , Privitera Grete , Pulvirenti Alfredo , Frasca Francesco

Background: Tyrosine kinase inhibitors (TKIs) are modern antineoplastic molecules widely used in the medical treatment of many cancers including iodine refractory differentiated thyroid carcer (DTC) and advanced medullary thyroid cancer (MTC). In patients with thyroid gland, TKIs frequently cause a destructive and/or autoimmune thyroiditis with consequent hypothyroidism. However, authors have reported unexpected TSH increase or hypothyroidism even in patients with total thyroi...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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